Sunday, June 25 1995
15.00 - 18.00 Registration Conference Center Lobby
18.00 - 18.30 Opening: Steven G. Gilbert Olympus Room
18.30 - 19.30 Speaker: Debbie Nickerson, Olympus Room
Neurotoxicology and Biotechnology-Future Directions
19:30 - 20.00 No Host Bar Cascade Tent
20.00 - ..... Opening Dinner Cascade Tent
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Monday, June 26 1995
7.30 - 8.45 Breakfast Bay View Room
Neurodegenerative Disorders and Environmental Chemicals
Chaired by: Deborah C. Rice and Bernard Weiss
9.00 - 9.15 Introduction: Annette Kirshner
& Steven G. Gilbert Olympus Room
9.15 - 9.50 Speaker: Bernard Weiss
The Latent Roots of Neurodegenerative Disease
9.50 - 10.30 Speaker: Stephanie Padilla
Organophosphate- Induced delayed neurotoxicity
(OPIDN). Facts and Fantasies
10.30 - 11.00 Tea and Coffee and Juice Conference Center Lobby
11.00 - 11.45 Speaker: Deborah C. Rice Olympus Room
Evidence for Delayed Methylmercury Neurotoxicity
in Monkey
11.45 - 12.30 Speaker: J. William Langston
MPTP: Implications for Neurotoxicants
and Neurodegenerative Disease
12.30 - 14.00 Lunch Cascade Tent
Monday, June 26 - continued
PCB Neurotoxicity
Chaired by: Ellen S. Goldey and Kevin M. Crofton
14.00 - 14.15 Introduction: Beverly Kulig Olympus Room
14.15 - 14.50 Speaker: Rich Seegal
Polychlorinated Biphenyls Decrease Dopamine and Elevate
GABA Content in Striatal Slices from Adult Rats
14.50 - 15.30 Speaker: Ellen S. Goldey
Developmental Exposure to Aroclor 1254 Causes
Hypothrodism and Low-Frequency Hearing Loss in Rats
15.30 - 16.10 Speaker: Dennis C. Morse
Alteration of Thyroid Hormone, Hemeostasis in
Relationship to Alterations in Neurochemical
Development Following Pre-and Postnatal PCB Exposure
16.15 - 16.45 Tea, Coffee and Soft Drinks Conference Center Lobby
16.45 - 17.00 Introduction: Lucio Costa and others Olympus Room
17.00 - 18.30 Speaker: Gerhard Winneke
Jacob Hooisma Lecture- Inorganic Lead as a Neurotoxicant
18.30 - 19.30 No Host Bar Bay View Room
19.30 - 20.30 Dinner Bay View Room
20.30 - ...... Discussion Leader: Kent Anger Olympus Room
Computerized Behavioral Testing of Humans
Tuesday, June 27 1995
7.30 - 8.45 Breakfast Bay View Room
Mechanisms, Neurotoxicity and Glial Cells
Chaired by: Michael Aschner and Lucio Costa
9.00 - 9.15 Introduction: Lucio Costa Olympus Room
9.15 - 9.50 Speaker: Michael Aschner
Astrocytes as Modulators of Mercury - Induced Neurotoxicity
9.50 - 10.30 Speaker: Pierre Morrell
The Schwann Cell as a Target for Neurotoxicity
10.30 - 11.00 Tea, Coffee and Juice Conference Center Lobby
11.00 - 11.45 Speaker: Donato DiMonte
Role of Glia in Neurotoxicant-Induced Parkinsonism
11.45 - 12.30 Speaker: Wolfgang J. Streit
The Role of Microglia in Brain Injury
12.30 - 14.00 Lunch Cascade Tent
Solvent Neurotoxicity - Poster Discussion Session
14.00 - 14.15 Introduction: Donna Mergler Olympus Room
14.15 - 15.15 Poster Discussion Participants -
Animal Models
(Romero, Heijink, Stoltenburg, Ray, Lund, Boyes)
15.15 - 15.45 Tea, Coffee and Soft Drinks Conference Center Lobby
15.45 - 16.45 Poster Discussion Participants - Olympus Room
Human Study
(Emmen, Muller, Williamson, Bergamaschi, Sassine)
17.00 - 19.00 Poster Session #1 Preview Cove Room
17.00 - 19.00 INA Executive Meeting Gazebo Room
19.00 - 20.30 Dinner and No Host Bar Cascade Tent
20.30 - ...... Poster Session #1 Cove Room
Wednesday, June 28 1995
6.30 - 7.45 Breakfast Bay View Room
8.00 Board Buses for Rain Forest Tour
8.10 Buses depart
9.30 Arrive Lake Crescent - Split into Groups
(Groups 1, 2, 3, 4, 5 - take cruise first;
Groups 6 and 7 - take nature walk first)
10.00 Boat departs; Walk begins
11.45 Boat returns; Walkers back; Box Lunch Delivered
12.00 Switch Groups:
2nd Boat group departs, groups 6 and 7;
2nd Nature walk group departs, groups 1- 5.
13.45 Everyone Returns
14.00 Board Buses
16.00 Arrive back at Port Ludlow
18.00 - 19.00 Refreshments Olympus Room and
Bay View Room
19.00 - 20.30 Formal Dinner Olympus Room
20.30 - 23.30 Dance with live band Bay View Room
Thursday, June 29 1995
7.30 - 8.45 Breakfast Bay View Room
Regulating Neurotoxicity: Laboratory to Risk Assessment
Chaired by: Ingeborg A. Ivens and Beverly Kulig
9.00 - 9.15 Introduction: Beverly Kulig Olympus Room
9.15 - 9.50 Speaker: Thomas J. Sobotka
FDA Guidelines for Neurotoxicological Testing
of Food Chemicals
9.50 - 10.30 Speaker: Huw B. Jones
Neuropathology in Risk Assessment of Xenobiotics
10.30 - 11.00 Tea, Coffee and Juice Conference Center Lobby
11.00 - 11.45 Speaker: Ingeborg A. Ivens Olympus Room
Investigations of Neurotoxicity Beyond Screening
11.45 - 12.30 Speaker: L. Simonsen
An Approach to Risk Assessment
12.30 - 14.00 Lunch Cascade Tent
14.00 - 17.00 Poster Session #2 Cove Room
16.30 - 17.00 Tea, Coffee and Soft Drinks Conference Center Lobby
17.00 - 19.00 INA General Business Meeting Olypmus Room
19.00 - 20.30 Dinner and No Host Bar Bay View Room
20.30 - ...... Discussion Leader: Abby A. Li Olympus Room
Neurotoxicity Testing: Are We on the Right Track?
20.30 - ...... Discussion Leader: Stanley Barone Jr. Elwha Room
Relevance of Neurotrophic Factors to Neurotoxicology
Friday, June 30 1995
7.30 - 8.45 Breakfast Bay View Room
New Developments In the Use of Neurotrophic Factors
in the Treatment of Neurodegenerative Disease
Chaired by: Brian Rogers and Carl LeBel
9.00 - 9.15 Introduction: Carl LeBel Olympus Room
9.15 - 9.45 Speaker: Stuart Apfel
Prospects for Using Neurotrophic Factors in the
Treatment and Prevention of Neurotoxicity: An Overview
9.45 - 10.15 Speaker: Brian Rogers
The Development of Recombinant Human Nerve Growth Factor
as a Treatment for Peripheral Neuropathic Disease
10.15 - 10.45 Tea, Coffee and Juice Conference Center Lobby
10.45 - 11.15 Speaker: Matthew Miller Olympus Room
Insulin-Like Growth Factor-I (Igf-I) Prevents
the Peripheral Neuropathy Induced by Vincristine,
Paclitaxel and Cisplatin
11.15 - 11.45 Speaker: Carl LeBel
Preclinical Profile of Recombinant Human Brain
Derived Neurotrophic Factor: Alternative Routes
of Delivery with this Potential Therapeutic for
Neurodegenerative Diseases
11.45 - 12.00 Closing Remarks: Steve Gilbert
12.00 - 13.00 Lunch and Close of Conference Patio of C